No probs Bill. 2a3 output ~3watts, 45 tube ~1.5watts. High effeciency drivers (ie tannoys, goodmans axioms, altec 604 or horn loaded compression drivers) are most suited to these tubes. But in saying that, I have never heard the ML3 with a SET so cant really comment further!
I have tried a extremely modded AudioNote 300B SET (8watts) with my old ML1 (86db) and at low volumes it was okay (70-80db), but when pushing it up to 'engaging' listening volumes, the bass would get too loose and muddy (just not enough power to control the 5" woofer). Valve amps distort differently to solid state so it doesn't sound deafening when it starts distorting, just mainly the clarity of bass and mid bass gets affected.
When I have my ML1 Ultra hooked up to flemo's Ming Da EL34 (40watt triode) push pull amp, compared to my Yaqin EL34 (20watt triode), the bass is so much stronger and cleaner with the Ming Da. This helps to improve the clarity of vocals too. At lowish volumes though, I find them to be similar in performance. But I prefer to listen at medium to high volumes!
Now when I hook up the killeramp (eL34 built by Steve's mate Paul Baker) 100watt pushpull, the ML1 ultras really shine then.. Mike's speakers are very hungry for strong clean power to get them to run their best! Look how big and thick those hand wound inductors are